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Plug in baby amp settings — Line 6 Spider 3

The Muse guitar tone for “Plug in baby”, dialed in for a Line 6 Spider 3 with a Ibanez GIO GRG170DX. Studio version, Origin of Symmetry (2001)

Original rig

Manson DeLorean (HH, built-in ZVex Fuzz Factory) → DigiTech Whammy → Diezel VH4 Channel 3 (or cranked Marshall)

Aggressive gated fuzz with tight low-end, searing upper-mids, and octave-up harmonic screech on the riff
Amp settings — Line 6 Spider 3
CHANNELInsane
GAIN 8 BASS 4 MID 6 TREBLE 7 REVERB 0 MASTER 5
KnobSetting (0–10)
Gain8
Bass4
Mid6
Treble7
Reverb0
Master5
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Guitar
PICKUPbridge TONE10 VOLUME10
Signal chain

01Fuzz Pedal (e.g., EHX Big Muff, Behringer SF300)

RECOMMENDED — not currently owned. The ZVex Fuzz Factory is essential to this tone; a Big Muff or cheap SF300 clone gets you 70% there with sustained fuzz, though you lose the gated sputtering character

Volume 7 · Tone 6 · Sustain 8

02DigiTech Whammy (or pitch shifter)

RECOMMENDED — not currently owned. Set to 2 octaves up, toe-down position for the iconic riff screech. Without this pedal, the riff loses its synth-like vocal quality entirely

Mode 2 OCT UP · Mix 10
Why these settings

The Spider 3's Insane channel is your closest match to the Diezel VH4's tight high-gain voicing. I've pushed mids to 6 (original was around 4-5 on the Diezel) because the Spider 3 is naturally scooped and fizzy in Insane mode—extra mids recover note definition. Bass dropped to 4 to tighten the low-end; the Spider's bass response is looser than the VH4's. Without a fuzz pedal, the amp gain alone will sound modern and saturated rather than gated and sputtering—this is a compromise.

PRO TIPThe riff is 16th notes at ~136 BPM with strict palm-muting except on the high notes—keep your picking hand anchored on the bridge and release muting only for the sustained high notes to get that machine-gun-to-scream contrast Bellamy nails.

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These settings are for a Line 6 Spider 3. ToneAdapt matches any song to whatever amp, guitar and pedals you own — first match is free.

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