Tone library / Derek and the dominos / Layla

Layla amp settings — Fender Mustang LT25

The Derek and the dominos guitar tone for “Layla”, dialed in for a Fender Mustang LT25 with a Squier Contemporary Stratocaster. Studio version, Layla and Other Assorted Love Songs (1970) - main opening riff

Original rig

1956 Fender Stratocaster ('Brownie') straight into a cranked 5W Fender Tweed Champ

Raw, compressed, mid-heavy tweed overdrive with biting single-coil attack

Amp settings — Fender Mustang LT25

CHANNEL'57 Champ amp modelBOOSToff

Knob	Setting (0–10)
Gain	8
Bass	6
Treble	7
Reverb	1
Master	7

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Guitar

PICKUPbridge TONE10 VOLUME10

Why these settings

Selecting the Mustang LT25's onboard '57 Champ model replicates the raw, sagging power-tube saturation of Clapton's cranked small tweed combo. Gain is pushed to 8 to capture that cranked-small-amp compression directly from the modeler without external pedals. The LT25 physical panel features Bass and Treble controls (no dedicated Middle or Presence knobs), so Treble is dialed to 7 to deliver the signature single-coil bite of 'Brownie'.

PRO TIPPick aggressively near the bridge saddles with medium-heavy attack to get that sharp, percussive snap on the opening descending riff.

Get this tone on your amp

These settings are for a Fender Mustang LT25. ToneAdapt matches any song to whatever amp, guitar and pedals you own — first match is free.

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More tones for the Fender Mustang LT25

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Song, artist and gear names are used to identify the tone being matched; ToneAdapt is not affiliated with or endorsed by the artists or manufacturers mentioned. Settings are AI-generated starting points — trust your ears.