Plug in baby amp settings — Line 6 Line 6

The Muse guitar tone for “Plug in baby”, dialed in for a Line 6 Line 6 with a Ibanez S521. Studio version, Origin of Symmetry (2001)

Original rig

Manson MB-1/DeLorean with built-in ZVex Fuzz Factory, DigiTech Whammy, cranked Marshall JCM800/Plexi

Aggressive gated fuzz with octave-up, thick saturated mids, synth-like screaming quality

Amp settings — Line 6 Line 6

CHANNELBrit Plexi Brt (amp model block)BRIGHTonBOOSToff

Knob	Setting (0–10)
Gain	6
Bass	5
Mid	7
Treble	7
Presence	6
Reverb	0
Master	7

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Guitar

PICKUPbridge TONE8 VOLUME10

Signal chain

01Arbitrator Fuzz (Helix block — ZVex Fuzz Factory model)

This is the closest Helix model to the Fuzz Factory. Gate control is critical for the sputtering, gated character. If Arbitrator unavailable, use Triangle Fuzz with Sustain at 8, Tone at 7

Fuzz 8 · Gate 6 · Comp 5 · Level 7

02Pitch Wham (Helix block — DigiTech Whammy model)

Set to +1 Octave mode. Heel down = dry, toe down = octave up. The main riff uses full toe-down octave effect

Position 10 · Mix 10

03Cab Block

Use 4x12 Greenback 25 IR. Low cut at 80Hz tightens the fuzz. High cut around 8kHz removes fizz

Model 0 · Low Cut 80 · High Cut 8

Why these settings

Your Ibanez S521 humbuckers are similar output to Bellamy's Manson pickups — no gain compensation needed. The Helix Brit Plexi Brt model replicates the cranked Marshall. I set amp gain at 6 rather than full crank because the Arbitrator Fuzz provides the primary saturation. Rolling tone knob to 8 tames the Ibanez's slightly brighter voicing versus the Manson.

PRO TIPThe iconic riff requires precise palm-muting pressure — too light and it loses aggression, too heavy and the octave tracking on the Whammy glitches. Practice the 16th-note run with your picking hand hovering just at the bridge saddles for that tight, percussive attack Bellamy gets.

Get this tone on your amp

These settings are for a Line 6 Line 6. ToneAdapt matches any song to whatever amp, guitar and pedals you own — first match is free.

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Song, artist and gear names are used to identify the tone being matched; ToneAdapt is not affiliated with or endorsed by the artists or manufacturers mentioned. Settings are AI-generated starting points — trust your ears.