Tone library / Derek & The Dominos / Layla

Layla amp settings — Boss Katana 50 MkII

The Derek & The Dominos guitar tone for “Layla”, dialed in for a Boss Katana 50 MkII with a Epiphone Les Paul Classic. Studio version, Layla and Other Assorted Love Songs (1970) — iconic opening riff and lead

Original rig

1956 Fender Stratocaster ('Brownie') straight into a cranked 1950s Fender Tweed Champ (5F1)

Cranked small-tweed tube compression with biting high-mids, singing sustain, and tight truncated bass

Amp settings — Boss Katana 50 MkII

CHANNELCrunch amp typeBOOSTon

Knob	Setting (0–10)
Gain	7
Bass	4
Mid	8
Treble	7
Reverb	2
Master	6

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Guitar

PICKUPbridge TONE8 VOLUME10

Why these settings

The Katana Crunch voice with the onboard Blues Driver boost engaged recreates the saturated breakup of a cranked 5W Tweed Champ pushed to its limits. To compensate for the Les Paul humbuckers versus Clapton's single-coil Strat, bass is dialed back to 4 to prevent low-end mud while mids are pushed to 8 for that cutting vocal bite. Presence is set to null because the Katana 50 MkII faceplate does not feature a physical presence knob.

PRO TIPPick forcefully near the bridge with medium-heavy attack to get the snappy, stinging transient response Clapton pulled out of the small Champ circuit.

Get this tone on your amp

These settings are for a Boss Katana 50 MkII. ToneAdapt matches any song to whatever amp, guitar and pedals you own — first match is free.

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Song, artist and gear names are used to identify the tone being matched; ToneAdapt is not affiliated with or endorsed by the artists or manufacturers mentioned. Settings are AI-generated starting points — trust your ears.